• Antimicrobial resistance due to the use of biocides and heavy metals: a literature review 

      Tronsmo, Arne; Gjøen, Tor; Sørum, Henning; Godfroid, Jacques; Yazdankhah, Siamak Pour; Jelmert, Anders; Klein, Joern; Okoli, Arinze Stanley; Ytrehus, Bjørnar; Skaar, Ida (Research report; Forskningsrapport, 2016-12-09)
      In June 2016,the Norwegian EnvironmentAgencyrequestedthe Norwegian Scientific Committee for Food Safety (VKM) to conducta literature reviewregardingdevelopment of bacterial resistance to biocides and heavy metals and cross-resistance to antimicrobial agents(e.g.,antibiotics)in bacteria, with the following mandate: <br><br>1.List chemical substancesthat may contribute to increased antimicrobial ...
    • Antimicrobial resistance in wildlife – potential for dissemination: Opinion of the Panel on Microbial Ecology of the Norwegian Scientific Committee for Food and Environment 

      Nielsen, Kaare Magne; Gjøen, Tor; Asare, Nana Yaa Ohene; Lunestad, Bjørn Tore; Ytrehus, Bjørnar; Yazdankhah, Siamak Pour; Godfroid, Jacques; Jelmert, Anders; Klein, Joern; Okoli, Arinze Stanley; Tronsmo, Arne (Research report; Forskningsrapport, 2018-03-16)
      <p>Antimicrobial resistance (AMR) is recognised as one of the greatest public health concerns of our time. The development of AMR occurs in nature as a defence by microbes against naturally occurring antimicrobials. However, the selective pressure, generated by the use of antimicrobial agents in human and veterinary medicine, livestock and plant production as well as aquaculture practices, is the ...
    • The genome sequence of Atlantic cod reveals a unique immune system 

      Star, Bastiaan; Nederbragt, Alexander Johan; Jentoft, Sissel; Grimholt, Unni; Malmstrøm, Martin; Gregers, Tone Fredsvik; Rounge, Trine Ballestad; Paulsen, Jonas; Solbakken, Monica Hongrø; Sharma, Animesh; Wetten, Ola Frang; Lanzén, Anders; Winer, Roger; Knight, James; Vogel, Jan-Hinnerk; Aken, Bronwen; Andersen, Øivind; Lagesen, Karin; Tooming-Klunderud, Ave; Edvardsen, Rolf; Kirubakaran, G. Tina; Espelund, Mari; Nepal, Chirag; Previti, A. Christopher; Karlsen, Bård Ove; Moum, Truls; Skage, Morten; Berg, Paul Ragnar; Gjøen, Tor; Kuhl, Heiner; Thorsen, Jim; Malde, Ketil; Reinhardt, Richard; Du, Lei; Johansen, Steinar Daae; Searle, Steve; Lien, Sigbjørn; Nilsen, Frank; Jonassen, Inge; Omholt, Stig W; Stenseth, Nils Christian; Jakobsen, Kjetill Sigurd (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-08-10)
      Atlantic cod (Gadus morhua) is a large, cold-adapted teleost that sustains long-standing commercial fisheries and incipient aquaculture1, 2. Here we present the genome sequence of Atlantic cod, showing evidence for complex thermal adaptations in its haemoglobin gene cluster and an unusual immune architecture compared to other sequenced vertebrates. The genome assembly was obtained exclusively by 454 ...
    • Health and environmental risk evaluation of microorganisms used in bioremediation. Scientific Opinion of the Panel on Microbial Ecology of the Norwegian Scientific Committee for Food Safety 

      Skaar, Ida; Asare, Nana Yaa Ohene; Godfroid, Jacques; Jelmert, Anders; Ytrehus, Bjørnar; Gjøen, Tor; Klein, Joern; Okoli, Arinze Stanley; Tronsmo, Arne (Research report; Forskningsrapport, 2016)
      In 2015, The Norwegian Environment Agency requested the Norwegian Scientific Committee for Food Safety (VKM) to collate an overview of bioremediation of polluted ground based on bioaugmentation described in literature for the degradation of various types of pollutants, (including hydrocarbons, heavy metals, chlorinated compounds, explosives etc.).The assessment of genetically modified microorganisms ...
    • Knowledge base for the assessment of environmental risks by the use of genetically modified virus-vectored vaccines for domesticated animals. Scientific Opinion of the Panel on Microbial Ecology of the Norwegian Scientific Committee for Food Safety 

      Okoli, Arinze Stanley; Asare, Nana Yaa Ohene; Gjøen, Tor; Klein, Joern; Ytrehus, Bjørnar (Research report; Forskningsrapport, 2016)
      The Norwegian Scientific Committee for Food Safety (VKM) was requested by the Norwegian Environment Agency in November 2015 to develop a knowledge base for assessment of the environmental risks related to the use of genetically modified (GM) virus vaccine vectors for vaccination of domesticated animals. The Agency requested that the task be conducted in the form of a desk study with the following ...
    • The use of light, restrictive feeding, fibrous feed and stocking density and the consequences for animal welfare for poultry species kept in Norway - Scientific Opinion of the Panel on Animal Health and Welfare of the Norwegian Scientific Committee for Food and Environment 

      Bøe, Knut Egil; Grahek-Ogden, Danica; Hoel, Kristian; Gjøen, Tor; Godfroid, Jacques Xavier Leon; Janczak, Andrew Michael; Madslien, Knut; Olsen, Rolf-Erik; Rimstad, Espen; Øverli, Øyvind; Agdestein, Angelika (Research report; Forskningsrapport, 2022-06-15)
    • ZN148 Is a Modular Synthetic Metallo-beta-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo 

      Samuelsen, Ørjan; Åstrand, Ove Alexander Høgmoen; Frøhlich, Christopher; Heikal, Adam; Skagseth, Susann; Carlsen, Trine Josefine Olsen; Leiros, Hanna-Kirsti S.; Bayer, Annette; Schnaars, Christian; Kildahl-andersen, Geir; Lauksund, Silje; Finke, Sarah; Huber, Sandra; Gjøen, Tor; Andresen, Adriana Magalhaes Santos; Økstad, Ole Andreas; Rongved, Pål (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-21)
      Carbapenem-resistant Gram-negative pathogens are a critical public health threat and there is an urgent need for new treatments. Carbapenemases (β-lactamases able to inactivate carbapenems) have been identified in both serine β-lactamase (SBL) and metallo-β-lactamase (MBL) families. The recent introduction of SBL carbapenemase inhibitors has provided alternative therapeutic options. Unfortunately, ...